DEERFIELD, Ill. — Walgreens will be cutting over 500 jobs, mostly at its headquarters here and its Chicago office.

About 10%, or 504, of the company’s corporate employees will be laid off, Walgreens spokesman Marty Maloney confirmed, noting that none of the staff at stores, micro-fulfillment centers, or call centers will be affected.

Maloney said the job cuts are not connected to financial liabilities. Walgreens Boots Alliance had a major operating loss in the first quarter as it pays out $6.5 billion in settlements related to the nationwide opioid crisis.

In a message to employees, chief executive officer Roz Brewer said the layoffs are needed “to drive sustainable cost savings to help fuel investments for future growth. …While difficult, these changes are necessary to streamline our business, unlock value and support our long-term goals.”